Patriarchate and Ministry
As patriarch, Gregory was active in the affairs of the eastern frontier during the long Roman war with Persia. He is credited with mediating when Roman troops under the emperor Maurice mutinied, and he met the Persian king Chosroes II when the latter fled to the Romans; afterward he received the cross that had earlier been carried off from Sergiopolis.
He was remembered as a gifted preacher and worked to bring non-Chalcedonian Christians to accept the definition of the Council of Chalcedon. Five of his homilies survive.