Confession and Trial
According to the synaxarion, Anicetus was provoked to open confession when Diocletian set up an implement of execution in the public square of Nicomedia to frighten the city's Christians. Rather than be intimidated, Anicetus denounced the emperor, and this public stand led to his arrest and to that of his nephew Photius.
The accounts of the saints' background differ. One tradition presents Anicetus as a military official of the city; another describes both men as physicians from a wealthy Christian family who practiced medicine without accepting payment or gifts, an 'unmercenary' manner of healing, on account of which Anicetus is numbered among the Holy Unmercenaries.