Family
Helena married King Stefan Uroš I of Serbia around 1245–1250. Her children included Stefan Dragutin, who reigned as Serbian king from 1276 to 1282; Stefan Uroš II Milutin, who reigned from 1282 to 1321; a further son named Stefan; and a daughter, Brnjača, who became a nun. Both Dragutin and Milutin are venerated as saints, and Helena is most commonly identified in the synaxarion as their mother.
Her own parents are recorded as John Angelos of Syrmia and Matilda of Požega. While her hagiographer Archbishop Danilo II describes her family as French, modern genealogical research has proposed descent through these parents from the Byzantine House of Angelos and the Hungarian House of Árpád.