The Thirteen Syrian Fathers
Saint Jesse belonged to the Thirteen Syrian Fathers, a company of monastic missionaries who, according to the tradition, came to Georgia in the sixth century under the leadership of Saint John of Zedazeni. The accounts describe Jesse as originating from Antioch and arriving in Georgia as one of John's companions.
The mission of these fathers is associated with the strengthening of Christianity in Georgia, and Jesse's own episcopate at Tsilkani is remembered as part of that wider missionary effort.